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Treating certain types of cancer. It is also used to control severe psoriasis and severe rheumatoid arthritis. Methotrexate is an antimetabolite that blocks an enzyme important in DNA synthesis. This slows the rate of cell production and development in tissues, which are growing at an abnormally fast rate. How Methotrexate works in rheumatoid arthritis is not completely understood. It may suppress the immune system, which produces chemicals causing inflammation (eg, swelling, pain, stiffness, warmth) of rheumatoid arthritis. Methotrexate Price ComparisonDisplaying prices on products containing Methotrexate as an active ingredient. Columns with underlined headers are sortable.![]() Loading Prices... |